Bio-Age implements three peer-reviewed biological aging algorithms and combines them
with evidence-based lifestyle modifiers to produce a composite biological age estimate.
PhenoAge
Levine et al. (2018). Uses 9 blood biomarkers + chronological age to compute
a mortality-based phenotypic age. Based on NHANES III data, validated against
cause-specific mortality.
KDM Bio-Age
Klemera & Doubal (2006). Regresses multiple biomarkers against chronological age
to estimate biological age through optimal linear combination. Implemented with
NHANES reference parameters.
Homeostatic Dysregulation
Cohen et al. (2013). Measures Mahalanobis distance of biomarker values from
young-adult reference norms. Higher dysregulation ↔ accelerated aging.
Lifestyle Score
Derived from meta-analyses: Li et al. (2018) BMJ, Nyberg et al. (2020) BMJ.
Exercise, sleep, diet, stress, social ties, smoking, and alcohol modify biological age
by up to ±8 years.
⚠️ Disclaimer: This is an educational tool. Results are estimates based on
published algorithms applied to self-reported biomarkers. Not a medical diagnosis.
Consult a healthcare professional for clinical interpretation.